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Prof. Scapagnini expert speaker in nutrients and gene expression conference in London

Throught the day, Prof Scapagnini, shared his insights and research on the effects of nutrition on gene expressions: Nutritional signals that modulate ageing and health span: a complex regulatory network for nutrigenomics research. 

An extensive literature describes the positive impact of dietary phytochemicals on overall health and longevity. Although the exact mechanisms by which phytochemicals promote these effects remain to be elucidated, several reports have shown their ability to stimulate various mechanisms associated with ageing process, including modulation of NAD+/sirtuin pathway and xenobiotic metabolising enzymes. Dietary phytochemicals include a large group of non-nutrients compounds from a wide range of plant-derived foods and chemical classes. Over the last decade, remarkable progress has been made to realise that chronic, low-grade inflammation and redox unbalance are critical aspects for the development of age-related diseases. The conference was organised in collaboration with BANT (British Association for Applied Nutrition & Nutritional Therapy).

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Orgaia’s Prof Giovanni Scapagnini regular expert guest on RAI TV’s Health & Science programme

The President of the Scientific Board of Orgaia, Prof. Giovanni Scapagnini has returned to RAI TV as the regular expert guest of the weekly health & science programme broadcast at prime time on Saturday mornings.

RAI is Italy’s National TV Network. The programme titled BUONGIORNO BENESSERE (Wellbeing Morning) includes a live studio audience and focuses on the latest scientific discoveries in nutrition, wellbeing and beauty. Italy is the first country in Europe in terms of longevity.

In the first episode of the new TV series Prof. Scapagnini talks about extending longevity and Telomere and Chomosome integrity thanks to the effects of the Mediterranean Diet. During the programme Prof. Scapagnini also developed a live experiment to demonstrate the positive effects of anti-inflammatory and antioxidant natural ingredients.

To view the video highlights of the first programme. Click on Video below.

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Prof Scapagnini Speaks at Hong Kong Forum on Chronic Disease

Orgaia’s Professor Giovanni Scapagnini attended the FORUM on ‘Nutritional problems and solutions for Modern Disease Epidemics’ in Hong Kong, China.

Organised by the Chinese Government and Prof Kang of Harvard University the conference focused on the global burden of chronic disease and the need to discuss urgent topics to identify viable solutions. Topics such as, healthcare system challenges, sugar intake and chronic disease. Prof Scapagnini presented on the topic of NUTRIGENIOMICS AND PERSONALISED NUTRITION. His presentation was on ‘Xenohormetic Nutrient signals that modulate Aging: a complex regulatory network for nutrigenomics research’.

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Okinawa Diet: Secret to Longevity

Orgaia’s Professor Giovanni Scapagnini attended the FOOD, WATER and HEALTH conference in VENICE, ITALY where he presented THE OKINAWA DIET – SECRET TO LONGEVITY.

The FOOD, WATER and HEALTH conference was organised by the Umberto Veronesi Foundation.

The event presented insights into health topics related to water and food, starting from the contribution that science can give for improving access to drinking water and more nutritious foods in developing countries. There is increasing interest in the link between our diets and modern health problems, such as obesity, cardiovascular disease and cancer.

The conference discussed how our diet has evolved over the past four million years and the evidences suggesting that our health problems are due to a mismatch between the hunter-gatherers diet (Paleolithic diets) and how our genome is best adapted to and our modern post-agricultural diet (Neolithic diet). The event presented a snapshot of the epidemic diffusion of chronic diseases in our society and the research goals of nutrigenomics, the science concerned with the relationships between nutrients, human genome and health. Food is not only energy for life. The nature of food preferences was also explored. How do our taste genes shape our diet? Which factors influence our perception and enjoyment of food and drink? How is food perceived in different cultures? The conference addressed the importance of a healthy diet rich in food bio-actives to prevent chronic diseases and promote healthy aging, with a special focus on the emerging role of intestinal microbiota in our health.

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Nutrigenomics: New Perspectives for a Nutraceutical Personalised Approach

Orgaia’s Prof Giovanni Scapagnini gave a keynote address on INNOVATION at the ‘Global trends, Regulation and Innovation in Food Supplements’ Summit in Italy.

His talk covered the topic:

The global food supplement market is estimated to reach 250 billion$ in 2018 with a CAGR of 7% over the forecast period. The key drivers of growth will be related to increasing consumer awareness and education on the role of food supplements as part of a balanced, healthy lifestyle, allowing consumers to make better-informed choices. Overwhelming evidence now supports the effects of food supplements – concentrates of important nutrients such as vitamins, minerals, amino and fatty acids and other substances with a nutritional or physiological effect – in various life stages.

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Prof Scapagnini Part of Scientific Committee of Nutraceuticals Event at Milan World Expo

Orgaia’s Prof. Scapagnini joined other world class scientists at the MILAN WORLD EXPO. Prof Scapagnini gave a talk on Nutraceuticals and brain protection as part of his role of Member of the Scientific Committee of the conference.

Nutraceuticals today are no longer just “food supplements”. They are among the main fighters against cardio-metabolic risk factors. Products such as extracts of red rice, phytosterols and omega-3 fish are ideal for a wide segment of the population that needs a preventive intervention for moderate alterations of cholesterol / triglycerides. For hypertensive people they offer amazing results using beet juice, bitter chocolate and its extracts: flavanols. But nutraceuticals have now achieved goals far more extensive. Today the prevention and treatment of early forms of macular degeneration, the eye disease of blindness in the elderly, is dramatically improved with the use of nutraceuticals. Such is the case of joint diseases and food integrators in sports, which avoids the risk of potential doping. Nutraceuticals also differentiate gender needs and requirements, with treatments directed to pregnancy, breastfeeding and menopause. Nutraceuticals also target areas where pharma has failed. Among these some neurological diseases, in particular Alzheimer’s disease, faced with new perspectives, different from ineffective therapies of anti beta-amyloids. They also offer important innovations in the treatment of obesity.

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Orgaia to Develop Innovative Natural Sweeteners

Orgaia is in the planning stages to work on developing new natural functional sweeteners and sugar substitutes.

This project is in response to the global diabetes and obesity epidemic and the great need to find sweetener alternatives to sugar with low calories that carry new added functionalities.

These ‘functional sweeteners’ project will use Orgaia’s NaturaGenomics™ philosophy and science deriving its innovation from Orgaia’s great expertise in integrating nature and nutrigenomics knowledge.

“It is clear now, that caloric restriction is vital to longevity but people want sweetness in their lives. It is how we balance these two ideas that can make a difference. We are now in the early stages of the new generation of sweetener development in the food industry. At Orgaia we are passionate about truly innovating by providing a sweetener that carries major functional properties based from nature”

said Nicolas de Santis, CEO of Orgaia.

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Brain, Heart, Cancer: Healing with the Power of Foods

Orgaia’s Professor Giovanni Scapagnini gave a talk on: ‘Brain, heart, cancer: healing with the power of foods’ at the FESTIVAL OF SCIENCE & MEDICINE FOR A LONGER LIFE.

Eating healthy does not mean only eating unadulterated or contaminated foods, or avoiding foods that damage organs over time with the consequent loss of functionality and widespread damage. It also means to choose foods that improve metabolism and prevent diseases while reducing harmful medicines. It is now also possible to use individual genetic predispositions to choose the ideal diet to preserve health.

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Orgaia’s Top Scientist Chairs NY Roundtable on Mediterranean Diet with focus on longevity

The President of Orgaia’s Scientific Board, Prof. Giovanni Scapagnini, Phd in Neurobiology, was the Chair of the Mediterranean Diet Roundtable Summit held in New York on 9th April 2015

Organised by global scientific leaders, the Mediterranean Diet Roundtable is an exclusive networking event bringing together the entire spectrum of decision-makers in the U.S. Food Industry, along with Doctors, Nutritionists, and Directors of Food Service programs. The goal of the event was to address the important topic of providing Mediterranean food choices, to grant a balanced diet in structures such as schools, hospitals, cafeterias, seniors’ centers, as well as stores. Research has shown that the traditional Mediterranean Diet reduces the risk of certain illnesses such as heart disease and cancer among others. A team of leading experts and professionals discussed all levels of Mediterranean nutrition aspects, menu’s engineering, stores and cafeteria strategies. Prof Giovanni Scapagnini was part of the key discussion on ageing Diet, Health and Longevity: Scientific Evidence of the Mediterranean Diet” that included leading experts such as Artemis P. Simopoulos, M.D. (Founder, Center for Genetics, Nutrition and Health) and Dr. Tara Narula, M.D. (Cardiologist at Lenox Hill Hospital and CBS Health News Contributor).

Prof Scapagnini of Orgaia and Chair of the event said:

“With obesity growing as a major real problem around the world and with the food and drinks industry being a huge business, the event focused on the positive impact of what the Mediterranean Diet can have on health, longevity and the well-being of society while dealing with major non communicable diseases such as cancer, obesity and diabetes.”

Improving Longevity

The Mediterranean Diet is a path to longevity with numerous studies showing that it protects from heart disease and cancer, top causes of death in the western world. Many Mediterranean countries have the highest life expectancies in the world. The Italian island of Sardinia and the Greek island of Ikaria are two of the five identified blue zones in the world. A blue zone is a location in which its inhabitants live much longer lives. This may be attributed to genes but also to the Mediterranean diet and lifestyle: plant based diet, physical activity and plenty of social contact. The Mediterranean diet includes certain “ingredients” that have been associated consistently with longevity, better heart and cognitive health. The “longevity ingredients” in this eating pattern are vegetables, plants in the form of greens and herbs, legumes, fish, dairy from free-range animals, olive oil as the main source of fat, very little meat and a bit of alcohol.

Last year a comprehensive literature review conducted by Italian researchers on an overall population of over 4,000,000 showed that a Mediterranean diet can reduce risk of death by 8%. The EPIC Elderly Study which included information of over 74,000 Europeans showed that adherence to a Mediterranean diet was associated with lower cause mortality. Another study that analyzed and compared the diets of centenarians from the Sicani Mountains in Sicily who had a close adherence to the Mediterranean diet with those of Palermo residents who were following a more westernized diet, found that adherence to the diet had a significant effect on mortality. It was noted that low animal protein, low glycemic index and high polyphenol content regulates and influences certain pathways and chemicals of the body that are involved in longevity. Strategies on how to incorporate the Mediterranean diet and lifestyle for a US population were discussed at the roundtable.

Sergio Davinelli, Scientific Board Member of Orgaia, and member of the Department of Medicine and Health Sciences, University of Molise, Italy, who also attended the event, said:

“The Mediterranean Diet is recognized by UNESCO as an Intangible Cultural Heritage of many countries, in truth it cannot be codified as a unique set of recipes and food patterns. Most people know by now what its main philosophy is and its main components are, i.e., the use of olive oil, rich in monounsaturated fats, the abundant use of legumes, fresh vegetables and fruits, some dairy products, lots of fish, little meat, and a surprising variety of cereals, used in many different ways. We at Orgaia believe such diet can become a huge asset in improving global health and nutritional education while reducing the obesity epidemic humanity faces”.

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